Actin-binding proteins.
نویسندگان
چکیده
Actin is an essential component of the cytoskeleton and plays a crucial role in eukaryotic cells. The actin cytoskeleton functions in the generation and maintenance of cell morphology and polarity, in endocytosis and intracellular trafficking, in contractility, motility and cell division. In cells, the assembly and disassembly of actin filaments, and also their organisation into functional higherorder networks, is regulated by a plethora of actin-binding proteins (ABPs) (dos Remedios et al., 2003; Maciver, 2004). The activities of these proteins are in turn under the control of specific signalling pathways.
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عنوان ژورنال:
- Journal of cell science
دوره 118 Pt 4 شماره
صفحات -
تاریخ انتشار 2005